Mississippi has one of the highest rates of sexually transmitted infections (STIs) in the U.S. according to 2023 CDC data. Rates of chlamydia in Mississippi – 700 cases per 100,000 residents – are the highest of all 50 states. Possible causes of Mississippi’s high STI rate include lack of access to health clinics in rural areas.

Sexually transmitted infections (STIs) are infections you can get from having unprotected sex like chlamydia, gonorrhea, human papilloma virus (HPV), and human immunodeficiency virus (HIV).

Using a barrier during sex such as a condom or dental dam can protect you against STIs. STIs can be transmitted in sexual activities that involve the mouth, vagina, penis, or anus. You can also ensure that you and your sexual partner(s) are tested for STIs before having sex, and on a regular basis if you are not in a monogamous relationship.

Some STIs can be prevented by a vaccine or medication. For example, a vaccination is available to help prevent human papillomavirus (HPV) and medications like PrEP help prevent infection from Human Immunodeficiency Virus (HIV). People can talk to their healthcare provider or community clinic to learn more about personal risk factors and preventative measures for STIs.

Vaccines against many STIs like chlamydia and HIV are still being developed.